Wave Life Sciences Leadership

Gregory L. Verdine (born June 10, 1959) is an American chemical biologist, biotech entrepreneur, venture capitalist and university professor. He is a founder of the field of chemical biology, which deals with the application of chemical techniques to biological systems. His work has focused on mechanisms of DNA repair and cell penetrability.

Michael Panzara is a CMO at WAVE LIFE SCIENCES LTD., VP:Multiple Sclerosis & Immune Diseases at Genzyme, and Chief Medical Ofcr/Head:Therapeutics Discovery at WaVe Life Sciences Pte Ltd and is based in Greater Boston. He has worked as Franchise Lead, Neurology at WAVE LIFE SCIENCES LTD.; Instructor in Neurology at Harvard Medical School; and Assistant in Neurology at Mass General Hospital. Michael works or has worked as VP/Chief Medical Officer at BIOGEN INC. and Head:MS & Immune Diseases at Genzyme. He studied at Harvard T.H. Chan School of Public Health between 2000 and 2002, University of Pennsylvania between 1985 and 1989, and Trustees of the University of Pennsylvania/The.

Senior Research and development leader with 25 years of experience in research and development of nucleosides and nucleic acid based therapeutics including aptamers, siRNAs, ribozymes, antisense and mRNA. Recognized thought leader in application of various nucleic acid platform technologies from basic research and discovery to commercial products with strong track record of patents and publications. Areas of expertise include:

• Directed and performed research in various nucleic acid based therapeutics

• Co-invented Macugen, FDA approved aptamer drug for Age Related Macular Degeneration (AMD)

• Oligonucleotide design, nucleic acid modification, synthesis and large scale production of drugs to support clinical trials

• Invented and developed nucleic acid delivery technologies including targeted delivery, liposomes, polymer and conjugates

• Pharmaceutical process research and development and manufacturing

• Extensive experience in nanoparticles for delivering nucleic acids

• Strong analytical skills to characterize nucleic acids and various nanoparticles

• Communicating effectively and working collaboratively across broad range of functions and external collaborations

• Recruiting and leading high-performance research and development organizations

Paul Bolno is a President/CEO at WaVe Life Sciences Pte Ltd, Board Member at WaVe Life Sciences Pte Ltd, and Board Member at SQZ Biotech and is based in Boston, Massachusetts. He has worked as Director:Research at Two Rivers Water & Farming, Director of Research at Two River, and Head:Global Neuroscience Bd at GSK. Paul works or has worked as FELLOW at Drexel University College of Medicine. He studied at LeBow College of Business - Drexel University between 2002 and 2004, Drexel University - College of Business and Administration between 2002 and 2004, and MCP-Hahnemann University School of Medicine between 1996 and 2000.

Gregory L. Verdine (born June 10, 1959) is an American chemical biologist, biotech entrepreneur, venture capitalist and university professor. He is a founder of the field of chemical biology, which deals with the application of chemical techniques to biological systems. His work has focused on mechanisms of DNA repair and cell penetrability.

Gregory L. Verdine (born June 10, 1959) is an American chemical biologist, biotech entrepreneur, venture capitalist and university professor. He is a founder of the field of chemical biology, which deals with the application of chemical techniques to biological systems. His work has focused on mechanisms of DNA repair and cell penetrability.

Paul Bolno is a President/CEO at WaVe Life Sciences Pte Ltd, Board Member at WaVe Life Sciences Pte Ltd, and Board Member at SQZ Biotech and is based in Boston, Massachusetts. He has worked as Director:Research at Two Rivers Water & Farming, Director of Research at Two River, and Head:Global Neuroscience Bd at GSK. Paul works or has worked as FELLOW at Drexel University College of Medicine. He studied at LeBow College of Business - Drexel University between 2002 and 2004, Drexel University - College of Business and Administration between 2002 and 2004, and MCP-Hahnemann University School of Medicine between 1996 and 2000.