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The 100 Largest Companies In Missouri For 2024

By Chris Kolmar
Mar. 19, 2024

If you live in Missouri and you’re looking for a job, you have come to the right place.

Because, sure, you can google things like ‘biggest companies in Missouri’ and get a fairly long list of companies with a lot of employees, or perhaps that have the biggest names — but here, we bring you the companies with the most current employees that are actually headquartered in Missouri.

Below, we’ll give you a complete list of Missouri’s 100 largest companies, but first, here’s a look at the top 10:

  1. Ascension Michigan (Jobs)

  2. Panera Bread (Jobs)

  3. CCO HOLDINGS LLC (Jobs)

  4. Emerson (Jobs)

  5. Enterprise Holdings (Jobs)

  6. O’Reilly Auto Parts (Jobs)

  7. Centene (Jobs)

  8. Edward Jones (Jobs)

  9. Bass Pro Shops (Jobs)

  10. Central Bank (Jobs)

Ascension Michigan comes in at the top, with more current employees than any other company in the state. We’ll get to specifics in a moment; first, here’s a look at our methodology.

How we identified the biggest companies in Missouri

Here at Zippia we have developed a database of over 250,000 companies that spans the entire country.

For this report, we looked at the companies headquartered in Missouri with at least 100 employees. That left us with 1,342 companies.

We then ranked each company from most to least current employees to determine the biggest companies in Missouri.

As it turns out, Ascension Michigan looks to the be the biggest company in Missouri clocking in with 150,000 employees.

Now, check out how the 100 biggest companies in Missouri ranked.

Detailed List Of The 100 Biggest Companies In Missouri

Rank Company City Employees Jobs
1 Ascension Michigan Saint Louis 150,000 Jobs
2 Panera Bread Saint Louis 140,000 Jobs
3 CCO HOLDINGS LLC Saint Louis 93,700 Jobs
4 Emerson Saint Louis 83,500 Jobs
5 Enterprise Holdings Saint Louis 80,000 Jobs
6 O’Reilly Auto Parts Springfield 77,654 Jobs
7 Centene Saint Louis 65,000 Jobs
8 Edward Jones Saint Louis 49,000 Jobs
9 Bass Pro Shops Springfield 40,000 Jobs
10 Central Bank Jefferson City 37,162 Jobs
11 Zodiac Chesterfield 35,000 Jobs
12 Anheuser-Busch Saint Louis 30,849 Jobs
13 Hallmark Cards Kansas City 30,000 Jobs
14 BJC HealthCare Saint Louis 27,191 Jobs
15 Express Scripts Holding Saint Louis 26,600 Jobs
16 Cerner Kansas City 26,400 Jobs
17 Amdocs Chesterfield 26,200 Jobs
18 Monsanto Saint Louis 25,500 Jobs
19 University of Missouri System Columbia 22,918 Jobs
20 EarthGrains Baking Companies Inc Saint Louis 20,000 Jobs
21 Leggett & Platt Carthage 20,000 Jobs
22 Hardee’s Food Systems Inc Saint Louis 16,680 Jobs
23 Abengoa Chesterfield 15,260 Jobs
24 Mizzou Columbia 15,000 Jobs
25 Viasystems Group Saint Louis 14,854 Jobs
26 Schnucks Saint Louis 14,500 Jobs
27 Marston Ballwin 14,000 Jobs
28 Caleres Saint Louis 13,400 Jobs
29 Charter Corp. Saint Louis 12,313 Jobs
30 CoxHealth Springfield 12,100 Jobs
31 Saint Luke’s Health System Kansas City 12,000 Jobs
32 Electrical Components International Saint Louis 12,000 Jobs
33 Post Holdings Saint Louis 11,410 Jobs
34 Barry-Wehmiller Saint Louis 11,000 Jobs
35 Saint Louis Fc Fenton 10,100 Jobs
36 Université Gaston Berger Saint Louis 10,001 Jobs
37 Enterprise CarShare Clayton 10,001 Jobs
38 SSM Health Saint Louis 10,001 Jobs
39 Premium Retail Services Chesterfield 10,000 Jobs
40 Sigma-Aldrich Saint Louis 9,600 Jobs
41 FURNITURE BRANDS INTERNATIONAL INC Saint Louis 9,100 Jobs
42 Graybar Saint Louis 8,700 Jobs
43 Ameren Saint Louis 8,615 Jobs
44 MU Health Care Columbia 8,328 Jobs
45 Lockton Companies Kansas City 8,300 Jobs
46 Belden Saint Louis 8,100 Jobs
47 Energizer Holdings Saint Louis 7,500 Jobs
48 Alamo Rent A Car Saint Louis 7,500 Jobs
49 Mac Equipment, Inc. Kansas City 7,500 Jobs
50 KV Pharmaceutical Chesterfield 7,500 Jobs
51 TAMKO Building Products Joplin 7,500 Jobs
52 Isle of Capri Casinos Saint Louis 7,500 Jobs
53 FleishmanHillard Saint Louis 7,500 Jobs
54 Centaur Building Services Inc Saint Louis 7,500 Jobs
55 Stifel Financial Saint Louis 7,100 Jobs
56 Peabody Energy Saint Louis 7,100 Jobs
57 World Wide Technology Maryland Heights 7,000 Jobs
58 Jack Henry & Associates Monett 6,717 Jobs
59 Kansas City Southern Kansas City 6,655 Jobs
60 Mercy Children’s Hospital Kansas City 6,551 Jobs
61 Perficient Saint Louis 6,500 Jobs
62 Olin Clayton 6,400 Jobs
63 State of Missouri Jefferson City 6,250 Jobs
64 Aegion Chesterfield 6,200 Jobs
65 Rose International Chesterfield 6,000 Jobs
66 Edgewell Personal Care Chesterfield 5,900 Jobs
67 Mix Holdings Inc Kansas City 5,650 Jobs
68 Build-A-Bear Workshop Saint Louis 5,643 Jobs
69 Mers/Missouri Goodwill Industries Saint Louis 5,397 Jobs
70 Dierbergs Markets Chesterfield 5,001 Jobs
71 Utilimap Corporation Fenton 5,000 Jobs
72 Outsourcing Chesterfield 5,000 Jobs
73 REORGANIZED FLI INC Kansas City 5,000 Jobs
74 Whelan Security Saint Louis 5,000 Jobs
75 Drury Hotels Saint Louis 5,000 Jobs
76 John Q. Hammons Hotels & Resorts Springfield 5,000 Jobs
77 COOPER BUSSMANN INC Ellisville 4,999 Jobs
78 Commerce Bank Kansas City 4,766 Jobs
79 Peabody Holding Company Inc. Saint Louis 4,660 Jobs
80 SunEdison Semiconductor Saint Peters 4,400 Jobs
81 Maritz Global Events Fenton 4,250 Jobs
82 Maritz Fenton 4,250 Jobs
83 Interface Systems 4,094 Jobs
84 Enactus Springfield 4,051 Jobs
85 Hallmark Retail Llc Kansas City 4,000 Jobs
86 Food Giant Sikeston 3,978 Jobs
87 Arch Resources Saint Louis 3,790 Jobs
88 Cassidy Turley Creve Coeur 3,700 Jobs
89 CPC Logistics Chesterfield 3,700 Jobs
90 Shelter Insurance Columbia 3,631 Jobs
91 Bunzl Distribution Saint Louis 3,625 Jobs
92 UMB Bank Kansas City 3,608 Jobs
93 H&R Block Kansas City 3,600 Jobs
94 Contract Freighters Joplin 3,569 Jobs
95 Butler Manufacturing Kansas City 3,542 Jobs
96 RotoMetrics Eureka 3,500 Jobs
97 Patriot Coal Saint Louis 3,500 Jobs
98 Orscheln Farm & Home Moberly 3,500 Jobs
99 HNTB Kansas City 3,400 Jobs
100 Mallinckrodt Hazelwood 3,400 Jobs

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Author

Chris Kolmar

Chris Kolmar is a co-founder of Zippia and the editor-in-chief of the Zippia career advice blog. He has hired over 50 people in his career, been hired five times, and wants to help you land your next job. His research has been featured on the New York Times, Thrillist, VOX, The Atlantic, and a host of local news. More recently, he's been quoted on USA Today, BusinessInsider, and CNBC.

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